2024
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Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead
<div> <p>ACS Chem Biol. 2024 Apr 26. doi: 10.1021/acschembio.4c00024. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity"
<div> <p>ACS Pharmacol Transl Sci. 2024 Mar 6;7(4):1195-1196. doi: 10.1021/acsptsci.4c00095. eCollection 2024 Apr 12.</p> [...]
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Empowering Voices: Inspiring Women in Medicinal Chemistry
<div> <p>ACS Med Chem Lett. 2024 Mar 8;15(4):424-431. doi: 10.1021/acsmedchemlett.4c00097. eCollection 2024 Apr 11.</p> <p><b>ABSTRACT</b></p> [...]
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Astrocytic uptake of posttranslationally modified amyloid-β leads to endolysosomal system disruption and induction of pro-inflammatory signaling
<div> <p>Glia. 2024 Apr 17. doi: 10.1002/glia.24539. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells
<div> <p>Cell Rep. 2024 Apr 23;43(4):114089. doi: 10.1016/j.celrep.2024.114089. Epub 2024 Apr 13.</p> <p><b>ABSTRACT</b></p> <p [...]
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The Joint Vasculitis Registry in German-speaking countries (GeVas): subgroup analysis of 266 AAV-patients
<div> <p>Clin Exp Rheumatol. 2024 Apr 12. doi: 10.55563/clinexprheumatol/suxkyq. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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AKAP12 Overexpression Affects Cardiac Function via PDE8
<div> <p>Circ Res. 2024 Apr 12;134(8):1023-1025. doi: 10.1161/CIRCRESAHA.124.324475. Epub 2024 Apr 11.</p> <p><b>NO ABSTRACT</b></p> <p>PMID:<a [...]
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Coordinating activation of endo-lysosomal two-pore channels and TRP mucolipins
<div> <p>J Physiol. 2024 Apr;602(8):1623-1636. doi: 10.1113/JP283829. Epub 2024 Apr 10.</p> <p><b>ABSTRACT</b></p> <p [...]
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Generation and characterization of antagonistic anti-human CD39 nanobodies
<div> <p>Front Immunol. 2024 Mar 25;15:1328306. doi: 10.3389/fimmu.2024.1328306. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Treatment of Cerebral Histiocytosis With Low Dose of Cobimetinib: A Report of 2 Cases
<div> <p>Neurol Neuroimmunol Neuroinflamm. 2024 May;11(3):e200233. doi: 10.1212/NXI.0000000000200233. Epub 2024 Apr 8.</p> [...]
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Clinical Presentation and Outcome of Critically Ill Patients with Inflammatory Bowel Disease
<div> <p>Visc Med. 2024 Apr;40(2):75-81. doi: 10.1159/000537885. Epub 2024 Mar 20.</p> <p><b>ABSTRACT</b></p> <p [...]
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SARS-CoV-2 M<sup>pro</sup> oligomerization as a potential target for therapy
<div> <p>Int J Biol Macromol. 2024 Apr 4;267(Pt 1):131392. doi: 10.1016/j.ijbiomac.2024.131392. Online ahead of print.</p> [...]
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Mutual regulation of CD4+ T cells and intravascular fibrin in infections
<div> <p>Haematologica. 2024 Apr 4. doi: 10.3324/haematol.2023.284619. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages
<div> <p>Science. 2024 Apr 5;384(6691):eabo7027. doi: 10.1126/science.abo7027. Epub 2024 Apr 5.</p> <p><b>ABSTRACT</b></p> <p [...]
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OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage
<div> <p>J Clin Invest. 2024 Apr 1;134(7):e169428. doi: 10.1172/JCI169428.</p> <p><b>ABSTRACT</b></p> <p [...]
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CD19-targeted chimeric antigen receptor T cell therapy in two patients with multiple sclerosis
<div> <p>Med. 2024 Mar 22:S2666-6340(24)00114-4. doi: 10.1016/j.medj.2024.03.002. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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BCMA x CD3 T-cell engager in a patient with penta-refractory multiple myeloma and HIV: a clinical and immunological report
<div> <p>Haematologica. 2024 Mar 28. doi: 10.3324/haematol.2023.284917. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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IL-22 promotes liver regeneration after portal vein ligation
<div> <p>Heliyon. 2024 Mar 8;10(6):e27578. doi: 10.1016/j.heliyon.2024.e27578. eCollection 2024 Mar 30.</p> <p><b>ABSTRACT</b></p> <p [...]
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Phosphodiesterases 4B and 4D Differentially Regulate cAMP Signaling in Calcium Handling Microdomains of Mouse Hearts
<div> <p>Cells. 2024 Mar 8;13(6):476. doi: 10.3390/cells13060476.</p> <p><b>ABSTRACT</b></p> <p xmlns:xlink="http://www.w3.org/1999/xlink" [...]
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Benchmarking machine learning-based real-time respiratory signal predictors in 4D SBRT
<div> <p>Med Phys. 2024 Mar 27. doi: 10.1002/mp.17038. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation
<div> <p>Front Immunol. 2024 Mar 8;15:1365484. doi: 10.3389/fimmu.2024.1365484. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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The importance of Ca<sup>2+</sup> microdomains for the adaptive immune response
<div> <p>Biochim Biophys Acta Mol Cell Res. 2024 Mar 23;1871(5):119710. doi: 10.1016/j.bbamcr.2024.119710. Online ahead of print.</p> [...]
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Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging
<div> <p>Nat Aging. 2024 Apr;4(4):595-612. doi: 10.1038/s43587-024-00598-z. Epub 2024 Mar 22.</p> <p><b>ABSTRACT</b></p> <p [...]
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Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport
<div> <p>Acta Physiol (Oxf). 2024 Apr;240(4):e14126. doi: 10.1111/apha.14126. Epub 2024 Mar 22.</p> <p><b>ABSTRACT</b></p> <p [...]
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A protective effect of inflammatory bowel disease on the severity of sclerosing cholangitis
<div> <p>Front Immunol. 2024 Mar 6;15:1307297. doi: 10.3389/fimmu.2024.1307297. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Symmetrical Bispyridinium Compounds Act as Open Channel Blockers of Cation-Selective Ion Channels
<div> <p>ACS Pharmacol Transl Sci. 2024 Feb 15;7(3):771-786. doi: 10.1021/acsptsci.3c00308. eCollection 2024 Mar 8.</p> <p><b>ABSTRACT</b></p> [...]
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Empowering Voices: Inspiring Women in Medicinal Chemistry
<div> <p>J Med Chem. 2024 Mar 28;67(6):4251-4258. doi: 10.1021/acs.jmedchem.4c00493. Epub 2024 Mar 8.</p> <p><b>ABSTRACT</b></p> <p [...]
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Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1
<div> <p>PLoS One. 2024 Mar 8;19(3):e0298542. doi: 10.1371/journal.pone.0298542. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Corrigendum to "Lack of Gα<sub>i2</sub> proteins in adipocytes attenuates diet-induced obesity" [Mol Metab 40 (2020 Oct) 101029]
<div> <p>Mol Metab. 2024 Apr;82:101910. doi: 10.1016/j.molmet.2024.101910. Epub 2024 Mar 2.</p> <p><b>NO ABSTRACT</b></p> <p>PMID:<a [...]
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Purinergic enzymes on extracellular vesicles: immune modulation on the go
<div> <p>Front Immunol. 2024 Feb 15;15:1362996. doi: 10.3389/fimmu.2024.1362996. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Time-resolved role of P2X4 and P2X7 during CD8<sup>+</sup> T cell activation
<div> <p>Front Immunol. 2024 Feb 15;15:1258119. doi: 10.3389/fimmu.2024.1258119. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Roles of microbiota in pancreatic cancer development and treatment
<div> <p>Gut Microbes. 2024 Jan-Dec;16(1):2320280. doi: 10.1080/19490976.2024.2320280. Epub 2024 Feb 27.</p> <p><b>ABSTRACT</b></p> <p [...]
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All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines
<div> <p>Int J Mol Sci. 2024 Feb 11;25(4):2168. doi: 10.3390/ijms25042168.</p> <p><b>ABSTRACT</b></p> <p [...]
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The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice
<div> <p>Front Endocrinol (Lausanne). 2024 Feb 6;14:1251351. doi: 10.3389/fendo.2023.1251351. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Thymic Atrophy and Immune Dysregulation in Infants with Complex Congenital Heart Disease
<div> <p>J Clin Immunol. 2024 Feb 23;44(3):69. doi: 10.1007/s10875-024-01662-4.</p> <p><b>ABSTRACT</b></p> <p [...]
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Magnitude of Type I Interferon Responses by Plasmacytoid Dendritic Cells After TLR7 Stimulation Is Associated With Human Immunodeficiency Virus Type 1 (HIV-1) Reservoir Sizes in Cisgender Women With HIV-1 on Antiretroviral Therapy
<div> <p>J Infect Dis. 2024 Feb 22:jiae013. doi: 10.1093/infdis/jiae013. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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Lack of evidence of acute HEV infections as a sexually transmitted disease: Data from a German cohort of PrEP users
<div> <p>Braz J Infect Dis. 2024 Jan-Feb;28(1):103720. doi: 10.1016/j.bjid.2024.103720. Epub 2024 Feb 13.</p> <p><b>ABSTRACT</b></p> <p [...]
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Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity
<div> <p>ACS Pharmacol Transl Sci. 2024 Jan 19;7(2):493-514. doi: 10.1021/acsptsci.3c00313. eCollection 2024 Feb 9.</p> <p><b>ABSTRACT</b></p> [...]
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High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension
<div> <p>bioRxiv [Preprint]. 2024 Feb 4:2024.02.02.578526. doi: 10.1101/2024.02.02.578526.</p> <p><b>ABSTRACT</b></p> <p [...]
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Analytical and clinical validation of a multiplex PCR assay for detection of <em>Neisseria gonorrhoeae</em> and <em>Chlamydia trachomatis</em> including simultaneous LGV serotyping on an automated high-throughput PCR system
<div> <p>Microbiol Spectr. 2024 Mar 5;12(3):e0275623. doi: 10.1128/spectrum.02756-23. Epub 2024 Feb 12.</p> <p><b>ABSTRACT</b></p> <p [...]
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Corrigendum: PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease
<div> <p>Front Immunol. 2024 Jan 24;15:1369747. doi: 10.3389/fimmu.2024.1369747. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca<sup>2+</sup> concentrations
<div> <p>Front Immunol. 2024 Jan 22;15:1294357. doi: 10.3389/fimmu.2024.1294357. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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SARS-CoV-2 vaccination may mitigate dysregulation of IL-1/IL-18 and gastrointestinal symptoms of the post-COVID-19 condition
<div> <p>NPJ Vaccines. 2024 Feb 5;9(1):23. doi: 10.1038/s41541-024-00815-1.</p> <p><b>ABSTRACT</b></p> <p [...]
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An antigen-specific chimeric autoantibody receptor (CAAR) NK cell strategy for the elimination of anti-PLA2R1 and anti-THSD7A antibody-secreting cells
<div> <p>Kidney Int. 2024 Apr;105(4):886-889. doi: 10.1016/j.kint.2024.01.021. Epub 2024 Feb 2.</p> <p><b>NO ABSTRACT</b></p> <p>PMID:<a [...]
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Obesity and diabetes mellitus are associated with SARS-CoV-2 outcomes without influencing signature genes of extrapulmonary immune compartments at the RNA level
<div> <p>Heliyon. 2024 Jan 14;10(2):e24508. doi: 10.1016/j.heliyon.2024.e24508. eCollection 2024 Jan 30.</p> <p><b>ABSTRACT</b></p> <p [...]
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Spatial normalization for voxel-based lesion symptom mapping: impact of registration approaches
<div> <p>Front Neurosci. 2024 Jan 17;18:1296357. doi: 10.3389/fnins.2024.1296357. eCollection 2024.</p> <p><b>ABSTRACT</b></p> <p [...]
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Intestinal epithelia and myeloid immune cells shape colitis severity and colorectal carcinogenesis via High-mobility group box protein 1
<div> <p>J Crohns Colitis. 2024 Jan 29:jjae017. doi: 10.1093/ecco-jcc/jjae017. Online ahead of print.</p> <p><b>ABSTRACT</b></p> <p [...]
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High vaccination coverage and infection rate result in a robust SARS-CoV-2-specific immunity in the majority of liver cirrhosis and transplant patients: A single-center cross-sectional study
<div> <p>United European Gastroenterol J. 2024 Apr;12(3):339-351. doi: 10.1002/ueg2.12528. Epub 2024 Jan 27.</p> <p><b>ABSTRACT</b></p> <p [...]
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DARTS: an open-source Python pipeline for Ca<sup>2+</sup> microdomain analysis in live cell imaging data
<div> <p>Front Immunol. 2024 Jan 11;14:1299435. doi: 10.3389/fimmu.2023.1299435. eCollection 2023.</p> <p><b>ABSTRACT</b></p> <p [...]
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PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease
<div> <p>Front Immunol. 2024 Jan 10;14:1326078. doi: 10.3389/fimmu.2023.1326078. eCollection 2023.</p> <p><b>ABSTRACT</b></p> <p [...]
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CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates <em>de novo</em> lipogenesis in adipose tissue
<div> <p>Front Immunol. 2024 Jan 9;14:1308456. doi: 10.3389/fimmu.2023.1308456. eCollection 2023.</p> <p><b>ABSTRACT</b></p> <p [...]
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Protocol for generating lung and liver metastasis in mice using models that bypass intravasation
<div> <p>STAR Protoc. 2024 Mar 15;5(1):102696. doi: 10.1016/j.xpro.2023.102696. Epub 2024 Jan 18.</p> <p><b>ABSTRACT</b></p> <p [...]
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Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis
<div> <p>Front Immunol. 2024 Jan 4;14:1258363. doi: 10.3389/fimmu.2023.1258363. eCollection 2023.</p> <p><b>ABSTRACT</b></p> <p [...]
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Mouse models of spontaneous liver and lung metastasis for colorectal cancer
<div> <p>STAR Protoc. 2024 Mar 15;5(1):102811. doi: 10.1016/j.xpro.2023.102811. Epub 2024 Jan 17.</p> <p><b>ABSTRACT</b></p> <p [...]
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Diagnostic and Therapeutic Radiopharmaceuticals: A "Hot" Topic
<div> <p>ACS Pharmacol Transl Sci. 2023 Dec 18;7(1):1-7. doi: 10.1021/acsptsci.3c00347. eCollection 2024 Jan 12.</p> <p><b>NO ABSTRACT</b></p> [...]
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Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice
<div> <p>J Nanobiotechnology. 2024 Jan 11;22(1):27. doi: 10.1186/s12951-023-02285-4.</p> <p><b>ABSTRACT</b></p> <p [...]
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EPAC1 enhances brown fat growth and beige adipogenesis
<div> <p>Nat Cell Biol. 2024 Jan;26(1):113-123. doi: 10.1038/s41556-023-01311-9. Epub 2024 Jan 9.</p> <p><b>ABSTRACT</b></p> <p [...]
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Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer's disease pathology
<div> <p>Mol Neurodegener. 2024 Jan 7;19(1):2. doi: 10.1186/s13024-023-00689-2.</p> <p><b>ABSTRACT</b></p> <p [...]
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Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2
<div> <p>Commun Biol. 2024 Jan 6;7(1):52. doi: 10.1038/s42003-023-05739-5.</p> <p><b>ABSTRACT</b></p> <p [...]
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Benefits of aHSCT over alemtuzumab in patients with multiple sclerosis besides disability and relapses: Sustained improvement in cognition and quality of life
<div> <p>Mult Scler Relat Disord. 2024 Feb;82:105414. doi: 10.1016/j.msard.2023.105414. Epub 2023 Dec 27.</p> <p><b>ABSTRACT</b></p> <p [...]
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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
<div> <p>Nat Commun. 2024 Jan 2;15(1):45. doi: 10.1038/s41467-023-44364-y.</p> <p><b>ABSTRACT</b></p> <p [...]
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Suberin, the hallmark constituent of bark, identified in a 45-million-year-old monkeyhair tree (Coumoxylon hartigii) from Geiseltal, Germany
<div> <p>Sci Rep. 2024 Jan 2;14(1):118. doi: 10.1038/s41598-023-50402-y.</p> <p><b>ABSTRACT</b></p> <p [...]
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Septins provide microenvironment sensing and cortical actomyosin partitioning in motile amoeboid T lymphocytes
<div> <p>Sci Adv. 2024 Jan 5;10(1):eadi1788. doi: 10.1126/sciadv.adi1788. Epub 2024 Jan 3.</p> <p><b>ABSTRACT</b></p> <p [...]
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Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca<sup>2+</sup> signals between lysosomes and the endoplasmic reticulum
<div> <p>Cell Rep. 2024 Jan 23;43(1):113628. doi: 10.1016/j.celrep.2023.113628. Epub 2023 Dec 30.</p> <p><b>ABSTRACT</b></p> <p [...]
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IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction
<div> <p>J Hepatol. 2024 Apr;80(4):634-644. doi: 10.1016/j.jhep.2023.12.015. Epub 2023 Dec 30.</p> <p><b>ABSTRACT</b></p> <p [...]
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The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
<div> <p>Dev Cell. 2024 Feb 5;59(3):308-325.e11. doi: 10.1016/j.devcel.2023.12.002. Epub 2023 Dec 29.</p> <p><b>ABSTRACT</b></p> <p [...]
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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection
<div> <p>Immunity. 2024 Jan 9;57(1):124-140.e7. doi: 10.1016/j.immuni.2023.11.018. Epub 2023 Dec 28.</p> <p><b>ABSTRACT</b></p> <p [...]
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Microglial TNFR2 signaling regulates the inflammatory response after CNS injury in a sex-specific fashion
<div> <p>Brain Behav Immun. 2024 Feb;116:269-285. doi: 10.1016/j.bbi.2023.12.025. Epub 2023 Dec 22.</p> <p><b>ABSTRACT</b></p> <p [...]
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Endolysosomal TRPML1 channel regulates cancer cell migration by altering intracellular trafficking of E-cadherin and β<sub>1</sub>-integrin
<div> <p>J Biol Chem. 2024 Jan;300(1):105581. doi: 10.1016/j.jbc.2023.105581. Epub 2023 Dec 21.</p> <p><b>ABSTRACT</b></p> <p [...]
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Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes
<div> <p>Nature. 2024 Jan;625(7994):385-392. doi: 10.1038/s41586-023-06857-0. Epub 2023 Dec 20.</p> <p><b>ABSTRACT</b></p> <p [...]
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Remodelling of cAMP dynamics within the SERCA2a microdomain in heart failure with preserved ejection fraction caused by obesity and type 2 diabetes
<div> <p>Cardiovasc Res. 2024 Mar 14;120(3):273-285. doi: 10.1093/cvr/cvad178.</p> <p><b>ABSTRACT</b></p> <p [...]
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Preoperative TIPS and in-hospital mortality in patients with cirrhosis undergoing surgery
<div> <p>JHEP Rep. 2023 Sep 23;6(1):100914. doi: 10.1016/j.jhepr.2023.100914. eCollection 2024 Jan.</p> <p><b>ABSTRACT</b></p> <p [...]
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Functional Inhibition of Katanin Affects Synaptic Plasticity
<div> <p>J Neurosci. 2024 Mar 27;44(13):e0374232023. doi: 10.1523/JNEUROSCI.0374-23.2023.</p> <p><b>ABSTRACT</b></p> <p [...]
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Feasibility and performance of cross-clone Raman calibration models in CHO cultivation
<div> <p>Biotechnol J. 2024 Jan;19(1):e2300289. doi: 10.1002/biot.202300289. Epub 2023 Dec 7.</p> <p><b>ABSTRACT</b></p> <p [...]
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E. coli´s fight against TYROnny: Designing a bacterial strain to tackle tyrosinemia type 1
<div> <p>J Hepatol. 2024 Mar;80(3):394-396. doi: 10.1016/j.jhep.2023.11.010. Epub 2023 Nov 24.</p> <p><b>NO ABSTRACT</b></p> <p>PMID:<a [...]
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Nmes1 is a novel regulator of mucosal response influencing intestinal healing potential
<div> <p>Eur J Immunol. 2024 Feb;54(2):e2350434. doi: 10.1002/eji.202350434. Epub 2023 Nov 28.</p> <p><b>ABSTRACT</b></p> <p [...]
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Multimodal characterization of dilated cardiomyopathy: Geno- And Phenotyping of PrImary Cardiomyopathy (GrAPHIC)
<div> <p>ESC Heart Fail. 2024 Feb;11(1):541-549. doi: 10.1002/ehf2.14544. Epub 2023 Nov 15.</p> <p><b>ABSTRACT</b></p> <p [...]
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Intestinal damage is required for the pro-inflammatory differentiation of commensal CBir1-specific T cells
<div> <p>Mucosal Immunol. 2024 Feb;17(1):81-93. doi: 10.1016/j.mucimm.2023.11.001. Epub 2023 Nov 10.</p> <p><b>ABSTRACT</b></p> <p [...]
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Diet and immune response: how today's plate shapes tomorrow's health
<div> <p>Trends Immunol. 2024 Jan;45(1):4-10. doi: 10.1016/j.it.2023.10.010. Epub 2023 Nov 8.</p> <p><b>ABSTRACT</b></p> <p [...]
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Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive individuals
<div> <p>Alzheimers Dement. 2024 Feb;20(2):1166-1174. doi: 10.1002/alz.13528. Epub 2023 Nov 3.</p> <p><b>ABSTRACT</b></p> <p [...]
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Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients
<div> <p>J Hepatol. 2024 Jan;80(1):109-123. doi: 10.1016/j.jhep.2023.10.009. Epub 2023 Oct 19.</p> <p><b>ABSTRACT</b></p> <p [...]
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Stereocontrolled access to thioisosteres of nucleoside di- and triphosphates
<div> <p>Nat Chem. 2024 Feb;16(2):249-258. doi: 10.1038/s41557-023-01347-2. Epub 2023 Oct 19.</p> <p><b>ABSTRACT</b></p> <p [...]
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Early Initiation of Antiretroviral Therapy Preserves the Metabolic Function of CD4+ T Cells in Subtype C Human Immunodeficiency Virus 1 Infection
<div> <p>J Infect Dis. 2024 Mar 14;229(3):753-762. doi: 10.1093/infdis/jiad432.</p> <p><b>ABSTRACT</b></p> <p [...]
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<em>HLA-DPA1*02:01~B1*01:01</em> is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells
<div> <p>Gut. 2024 Jan 5;73(2):325-337. doi: 10.1136/gutjnl-2023-329524.</p> <p><b>ABSTRACT</b></p> <p [...]
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Does gamma-glutamyltransferase correlate with liver tumor burden in neuroendocrine tumors?
<div> <p>Endocrine. 2024 Feb;83(2):511-518. doi: 10.1007/s12020-023-03545-x. Epub 2023 Sep 28.</p> <p><b>ABSTRACT</b></p> <p [...]
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IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in Mice
<div> <p>Cell Mol Gastroenterol Hepatol. 2024;17(1):79-91. doi: 10.1016/j.jcmgh.2023.09.006. Epub 2023 Sep 19.</p> <p><b>ABSTRACT</b></p> <p [...]
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Inosine: novel activator of brown adipose tissue and energy homeostasis
<div> <p>Trends Cell Biol. 2024 Jan;34(1):72-82. doi: 10.1016/j.tcb.2023.04.007. Epub 2023 May 13.</p> <p><b>ABSTRACT</b></p> <p [...]