2019

Josts, I., Veith, K. & Tidow, H. Ternary structure of the outer membrane transporter FoxA provides insights into TonB-mediated siderophore uptake. eLife 8, e48528 (2019)

Johnsen B, Kaschubowski KE, Nader S, Schneider E, Nicola JA, Fliegert R, Wolf IMA, Guse AH, Nikolaev VO, Koch-Nolte F, Haag F. P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP. Purinergic Signal. 2019 Apr 23

Rotermund N, Schulz K, Hirnet D, Lohr C. Purinergic Signaling in the Vertebrate Olfactory System. Front Cell Neurosci. 2019 Apr 16;13:112.

J. Harberts, R. Zierold, C. Fendler, A. Koitmäe, P. Bayat, I. Fernandez-Cuesta, G. Loers, B.-P. Diercks, R. Fliegert, A.H. Guse, C. Ronning, G. Otnes, M. Borgström, R.H. Blick, Culturing and patch clamping of Jurkat T cells and neurons on Al 2 O 3 coated nanowire arrays of altered morphology, RSC Adv. 9 (2019) 11194–11201.

Baszczyňski O, Watt JM, Rozewitz MD, Guse AH, Fliegert R, Potter BVL. Synthesis of terminal ribose analogues of adenosine 5'-diphosphate ribose (ADPR) as probes for the Transient Receptor Potential (TRP) cation channel TRPM2. J Org Chem. 2019 Apr 12.

Hierweger AM, Engler JB, Friese MA, Reichardt HM, Lydon J, DeMayo F, Mittrücker HW, Arck PC. Progesterone modulates the T-cell response via glucocorticoid receptor-dependent pathways. Am J Reprod Immunol. 2019 Jan 2:e13084.

Landahl J, Bockmann JH, Scheurich C, Ackermann C, Matzat V, Heide J, Nuurei T, D'Antonio G, von Felden J, Sette A, Peine S, Lohse AW, Luetgehetmann M, Marget M, Sidney J, Schulze Zur Wiesch J. Detection of a Broad Range of Low-Level Major Histocompatibility Complex Class II-Restricted, Hepatitis Delta Virus(HDV)-Specific T-Cell Responses Regardless of Clinical Status.
J Infect Dis. 2019 Jan 29;219(4):568-577.

Linden J, Koch-Nolte F, Dahl G. Purine Release, Metabolism, and Signaling in the Inflammatory Response.
Annu Rev Immunol. 2019 Jan 24.

Puig B, Altmeppen HC, Linsenmeier L, Chakroun K, Wegwitz F, Piontek UK, Tatzelt J, Bate C, Magnus T, Glatzel M. GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice.
PLoS Pathog. 2019 Jan 4;15(1):e1007520.

Ludewig P, Winneberger J, Magnus T. The cerebral endothelial cell as a key regulator of inflammatory processes in sterile inflammation.
J Neuroimmunol. 2019 Jan 15;326:38-44.

oh L, Kang SW, Baik SH, Ng GYQ, She DT, Balaganapathy P, Dheen ST, Magnus T, Gelderblom M, Sobey CG, Koo EH, Fann DY, Arumugam TV. Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke.
Brain Behav Immun. 2019 Jan;75:34-47

Siracusa F, Schaltenberg N, Villablanca EJ, Huber S, Gagliani N. Dietary Habits and Intestinal Immunity: From Food Intake to CD4(+) T (H) Cells.
Front Immunol. 2019 Jan 15;9:3177.

Perna-Barrull D, Rodriguez-Fernandez S, Pujol-Autonell I, Gieras A, Ampudia-Carrasco RM, Villalba A, Glau L, Tolosa E, Vives-Pi M. Prenatal Betamethasone interferes with immune system development and alters target cells in autoimmune diabetes.
Sci Rep. 2019 Feb 4;9(1):1235.

Cordts K, Grzybowski R, Lezius S, Lüneburg N, Atzler D, Neu A, Hornig S, Böger RH, Gerloff C, Magnus T, Thomalla G, Schwedhelm E, Grant PJ, Choe CU. Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA(2)DS(2)-VASc score in three cross-sectional studies.
J Neurol Sci. 2019 Feb 15;397:156-161.

Siracusa F, Schaltenberg N, Villablanca EJ, Huber S, Gagliani N. Dietary Habits and Intestinal Immunity: From Food Intake to CD4(+) T (H) Cells. Front Immunol. 2019 Jan 15;9:3177

Fliegert R, Heeren J, Koch-Nolte F, Nikolaev VO, Lohr C, Meier C, Guse AH. Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation.
Biochem Soc Trans. 2019 Feb 28;47(1):329-337.

Diercks BP, Werner R, Schetelig D, Wolf IMA, Guse AH. High-Resolution Calcium Imaging Method for Local Calcium Signaling.
Methods Mol Biol. 2019;1929:27-39.

Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S. FOXK1 and FOXK2 regulate aerobic glycolysis.
Nature. 2019 Feb;566(7743):279-283.

Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C, Watanabe T, Schlosser C, Merlini A, Körner H, Chang HF, Fischer HJ, Reichardt HM, Zagrebelsky M, Mollenhauer B, Kügler S, Fitzner D, Frahm J, Stadelmann C, Haberl M, Odoardi F, Flügel A. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration.
Nature. 2019 Feb;566(7745):503-508.

Zuo H, Cattani-Cavalieri I, Musheshe N, Nikolaev VO, Schmidt M. Phosphodiesterases as therapeutic targets for respiratory diseases.
Pharmacol Ther. 2019 Feb 10. pii: S0163-7258(19)30015-4

Gnirck AC, Wunderlich M, Becker M, Xiong T, Weinert E, Meyer-Schwesinger C, Dumoutier L, Renauld JC, Huber S, Panzer U, Turner JE. Endogenous IL-22 is dispensable for experimental glomerulonephritis. Am J Physiol Renal Physiol. 2019 Feb 6.

Tintelnot J, Ufer F, Engler JB, Winkler H, Lücke K, Mittrücker HW, Friese MA. Arc/Arg3.1 defines dendritic cells and Langerhans cells with superior migratory ability independent of phenotype and ontogeny in mice.
Eur J Immunol. 2019 Feb 20.

linge S, Yan K, Reimers D, Brede KM, Schmid J, Paust HJ, Krebs CF, Panzer U, Hopfer H, Mittrücker HW. Role of regulatory T cells in experimental autoimmune glomerulonephritis.
Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F572-F581.

Kniep HC, Madesta F, Schneider T, Hanning U, Schönfeld MH, Schön G, Fiehler J, Gauer T, Werner R, Gellissen S. Radiomics of Brain MRI: Utility in Prediction of Metastatic Tumor Type.
Radiology. 2019 Feb;290(2):479-487.

Schreurs RRCE, Baumdick ME, Sagebiel AF, Kaufmann M, Mokry M, Klarenbeek PL, Schaltenberg N, Steinert FL, van Rijn JM, Drewniak A, The SML, Bakx R, Derikx JPM, de Vries N, Corpeleijn WE, Pals ST, Gagliani N, Friese MA, Middendorp S, Nieuwenhuis EES, Reinshagen K, Geijtenbeek TBH, van Goudoever JB, Bunders MJ. Human Fetal TNF-α-Cytokine-Producing CD4(+) Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life.
Immunity. 2019 Feb 19;50(2):462-476.e8.

Bischoff J, Boesecke C, Ingiliz P, Berger F, Simon KG, Lutz T, Schewe CK, Schulze Zur Wiesch J, Hueppe D, Christensen S, Mauss S, Baumgarten A, Rockstroh JK; GECCO study group. Has Increased Rollout of Direct Acting Antiviral Therapy Decreased the Burden of Late Presentation and Advanced Liver Disease in Patients Starting Hepatitis C Virus Therapy in Germany?
J Clin Gastroenterol. 2019 Feb 15.

Eiringhaus J, Herting J, Schatter F, Nikolaev VO, Sprenger J, Wang Y, Köhn M, Zabel M, El-Armouche A, Hasenfuss G, Sossalla S, Fischer TH. Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling.
Basic Res Cardiol. 2019 Feb 20;114(2):13.

Schreurs RRCE, Baumdick ME, Sagebiel AF, Kaufmann M, Mokry M, Klarenbeek PL, Schaltenberg N, Steinert FL, van Rijn JM, Drewniak A, The SML, Bakx R, Derikx JPM, de Vries N, Corpeleijn WE, Pals ST, Gagliani N, Friese MA, Middendorp S, Nieuwenhuis EES, Reinshagen K, Geijtenbeek TBH, van Goudoever JB, Bunders MJ. Human Fetal TNF-α-Cytokine-Producing CD4(+) Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life.
Immunity. 2019 Feb 19;50(2):462-476.e8.

Booz V, Christiansen CB, Kuhre RE, Saltiel MY, Sociali G, Schaltenberg N, Fischer AW, Heeren J, Zocchi E, Holst JJ, Bruzzone S. Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine.
Diabetes Metab Res Rev. 2019 Feb;35(2):e3102.

Worthmann A, Schlein C, Berbée JFP, Rensen PCN, Heeren J, Bartelt A. Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression.
Nutrients. 2019 Feb 23;11(2). pii: E463.

Fliegert R, Heeren J, Koch-Nolte F, Nikolaev VO, Lohr C, Meier C, Guse AH. Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation.
Biochem Soc Trans. 2019 Feb 28;47(1):329-337.

Jux B, Gosejacob D, Tolksdorf F, Mandel C, Rieck M, Namislo A, Pfeifer A, Kolanus W. Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion.
Sci Rep. 2019 Mar 5;9(1):3442.

Bastug-Özel Z, Wright PT, Kraft AE, Pavlovic D, Howie J, Froese A, Fuller W, Gorelik J, Shattock MJ, Nikolaev VO. Heart failure leads to altered β2-adrenoceptor/cyclic adenosine monophosphate dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain.
Cardiovasc Res. 2019 Mar 1;115(3):546-555.

Gold SM, Willing A, Leypoldt F, Paul F, Friese MA. Sex differences in autoimmune disorders of the central nervous system.
Semin Immunopathol. 2019 Mar;41(2):177-188.

Beiersdorfer A, Scheller A, Kirchhoff F, Lohr C. Panglial gap junctionsbetween astrocytes and olfactory ensheathing cells mediate transmission of Ca(2+) transients and neurovascular coupling.
Glia. 2019 Mar 18

Lahesmaa M, Oikonen V, Helin S, Luoto P, U Din M, Pfeifer A, Nuutila P, Virtanen KA. Regulation of human brown adipose tissue by adenosine and A(2A) receptors - studies with [(15)O]H(2)O and [(11)C]TMSX PET/CT.
Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):743-750.

Tintelnot J, Baum N, Schultheiss C, Braig F, Trentmann M, Finter J, Fumey W,Bannas P, Fehse B, Riecken K, Schütze K, Bokemeyer C, Rösner T, Valerius T, Peipp M, Koch-Nolte F, Binder M. Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies.
Mol Cancer Ther. 2019 Mar 1. pii: molcanther.0849.2018

Lühl L, Andrianov K, Dierks H, Haidl A, Dehlinger A, Heine M, Heeren J, Nisius T, Wilhein T, Kanngießer B. Scanning transmission X-ray microscopy with efficient X-ray fluorescence detection (STXM-XRF) for biomedical applications in the soft and tender energy range
J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):430-438.

Fischer AW, Schlein C, Cannon B, Heeren J, Nedergaard J. Intact innervation is essential for diet-induced recruitment of brown adipose tissue.
Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E487-E503.

Lemoine M, Assoumou L, De Wit S, Girard PM, Valantin MA, Katlama C, Necsoi C, Campa P, Huefner AD, Schulze Zur Wiesch J, Rougier H, Bastard JP, Stocker H,Mauss S, Serfaty L, Ratziu V, Menu Y, Schlue J, Behrens G, Bedossa P, Capeau J, Ingiliz P, Costagliola D; ANRS-ECHAM Group. Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
J Acquir Immune Defic Syndr. 2019 Apr 1;80(4):e86-e94.

Contact

University Medical Center Hamburg-Eppendorf 
Department of Biochemistry and Molecular Cell Biology 
Martinistrasse 52
20246 Hamburg

Scientific Coordinator

Dr. Björn-Philipp Diercks
Fon: +49  (0) 40 7410 54338
E-Mail: b.diercks©uke.de

Administration

Laura Mitsching
Fon: +49  (0) 40 7410 50301
E-Mail: l.mitsching©uke.de