2022

2022

Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, Kouassi NM, Beck S, Jaeckstein MY, Mann O, Krasemann S, Schroeder M, Jarczak D, Nierhaus A, Kluge S, Peschka M, Schlüter H, Renné T, Pueschel K, Kloetgen A, Scheja L, Ondruschka B, Heeren J, Gabriel G (2022) Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans. Cell Metab. 34:1-2.

Ruether DF*, Schaub GM*, Duengelhoef PM, Haag F, Brehm TT, Fathi A, Wehmeyer M, Jahnke-Triankowski J, Mayer L, Hoffmann A, Fischer L, Addo MM, Lütgehetmann M, Lohse AW, Schulze Zur Wiesch J, Sterneck M (2022) SARS-CoV2-specific Humoral and T-cell Immune Response After Second Vaccination in Liver Cirrhosis and Transplant Patients. Clin Gastroenterol Hepatol. 20:162-172.e9

Di Lauro C, Bianchi C, Sebastián-Serrano Á, Soria-Tobar L, Alvarez-Castelao B, Nicke A, Díaz-Hernández M (2022) P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies. Prog Neurobiol. 208:102173

Guse, A.H (2022) NAADP Signaling: New Kids on the Block. Cells 11, 1054. 

Gil D, Diercks BP, Guse AH, Dupont G (2022) Three-Dimensional Model of Sub-Plasmalemmal Ca2+ Microdomains Evoked by T Cell Receptor/CD3 Complex Stimulation. Front Mol Biosci. 9:811145. 

Riekehr WM, Sander S, Pick J, Tidow H, Bauche A, Guse AH, Fliegert R (2022) cADPR Does Not Activate TRPM2. Int J Mol Sci. 23:3163. 

Hosang L, Canals RC, van der Flier FJ, Hollensteiner J, Daniel R, Flügel A, Odoardi F (2022) The lung microbiome regulates brain autoimmunity. Nature. 603(7899):138-144.

Fearey BC, Binkle L, Mensching D, Schulze C, Lohr C, Friese MA, Oertner TG, Gee CE (2022) A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis. Sci Rep. 12(1):6000.

Kurelić R, Nikolaev VO (2022) Generation of Transgenic Mice Expressing Cytosolic and Targeted FRET Biosensors for cAMP and cGMP. Methods Mol Biol. 2483:241-254

Fischer AW, Jaeckstein MY, Heeren J (2022) Lysosomal acid lipase promotes endothelial proliferation in cold-activated adipose tissue. Adipocyte. 11(1):28-33

Dieckmann S, Strohmeyer A, Willershäuser M, Maurer SF, Wurst W, Marschall S, de Angelis MH, Kühn R, Worthmann A, Fuh MM, Heeren J, Köhler N, Pauling JK, Klingenspor M (2022) Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1. Am J Physiol Endocrinol Metab. 322(2):E85-E100.

IJzerman AP, Jacobson KA, Müller CE, Cronstein BN, Cunha RA (2022) International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update. Pharmacol Rev. 74(2):340-372

Schulte S, Heide J, Ackermann C, Peine S, Ramharter M, Mackroth MS, Woost R, Jacobs T, Schulze Zur Wiesch J (2022) Deciphering the Plasmodium falciparum malaria-specific CD4+ T-cell response: ex vivo detection of high frequencies of PD-1+TIGIT+ EXP1-specific CD4+ T cells using a novel HLA-DR11-restricted MHC class II tetramer. Clin Exp Immunol. 207(2):227-236

Worthmann A, Bartelt A (2022) MALDI MSI for a fresh view on atherosclerotic plaque lipids. Pflugers Arch. 474(2):185-186

Mühlig AK, Steingröver J, Heidelbach HS, Wingerath M, Sachs W, Hermans-Borgmeyer I, Meyer-Schwesinger C, Choi HY, Lim BJ, Patry C, Hoffmann GF, Endlich N, Bracke K, Weiß M, Guse AH, Lassé M, Rinschen MM, Braun F, Huber TB, Puelles VG, Schmitt CP, Oh J (2022) The calcium-sensing receptor stabilizes podocyte function in proteinuric humans and mice. Kidney Int. 101(6):1186-1199

Sander S, Pick J, Gattkowski E, Fliegert R, Tidow H (2022) The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+ -binding domain essential for structural integrity and channel activity. Protein Sci. 31(6):e4320

Boda E, Boscia F, Lohr C (2022) Editorial: The Role of Astroglia and Oligodendroglia in CNS Development, Plasticity, and Disease - Novel Tools and Investigative Approaches. Front Cell Neurosci. 16:901820

Kolbe K, Wittner M, Hartjen P, Hüfner AD, Degen O, Ackermann C, Cords L, Stellbrink HJ, Haag F, Schulze Zur Wiesch J (2022) Inversed Ratio of CD39/CD73 Expression on γδ T Cells in HIV Versus Healthy Controls Correlates With Immune Activation and Disease Progression. Front Immunol. 13:867167.

Kemming J, Gundlach S, Panning M, Huzly D, Huang J, Lütgehetmann M, Pischke S, Schulze Zur Wiesch J, Emmerich F, Llewellyn-Lacey S, Price DA, Tanriver Y, Warnatz K, Boettler T, Thimme R, Hofmann M, Fischer N, Neumann-Haefelin C (2022) Mechanisms of CD8+ T cell failure in chronic hepatitis E virus infection. J Hepatol. S0168-8278(22)00334-8

Schädlich IS, Schnapauff O, Pöls L, Schrader J, Tolosa E, Rissiek B, Magnus T (2022) Nt5edeficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model. iScience. 25(6):104470.

Beamer E, Morgan J, Alves M, Menéndez Méndez A, Morris G, Zimmer B, Conte G, de Diego-Garcia L, Alarcón-Vila C, Yiu Ng NK, Madden S, Calzaferri F, de Los Ríos C, García AG, Hamacher M, Dinkel K, Pelegrín P, Henshall DC, Nicke A, Engel T (2022) Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice. Br J Pharmacol. 179(12):2986-3006

Fischer AW, Jaeckstein MY, Heeren J. Lysosomal acid lipase promotes endothelial proliferation in cold-activated adipose tissue (2022) Adipocyte. 11(1):28-33

Hambach J, Fumey W, Stähler T, Gebhardt AJ, Adam G, Weisel K, Koch-Nolte F, Bannas P (2022) Half-Life Extended Nanobody-Based CD38-Specific Bispecific Killercell Engagers Induce Killing of Multiple Myeloma Cells. Front Immunol. 13:838406

Claff T, Klapschinski TA, Tiruttani Subhramanyam UK, Vaaßen VJ, Schlegel JG, Vielmuth C, Voß JH, Labahn J, Müller CE (2022) Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A2A Receptor with Preladenant Conjugates. Angew Chem Int Ed Engl. 61(22):e202115545

Cords L, Knapp M, Woost R, Schulte S, Kummer S, Ackermann C, Beisel C, Peine S, Johansson AM, Kwok WW-H, Günther T, Fischer N, Wittner M, Addo MM, Huber S, Schulze zur Wiesch J (2022) High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19. Viruses. 14(6):1265

 

Candelario-Jalil E, Dijkhuizen RM, Magnus T (2022) Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities. Stroke, online ahead of print

Claff T, Klapschinski TA, Tiruttani Subhramanyam UK, Vaaßen VJ, Schlegel JG, Vielmuth C, Voß JH, Labahn J, Müller CE (2022) Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A2A Receptor with Preladenant Conjugates. Angew Chem Int Ed Engl, online ahead of print

Anisimova M, van Bommel B, Wang R, Mikhaylova M, Simon Wiegert J, Oertner TG, Gee CE (2022) Spike-timing-dependent plasticity rewards synchrony rather than causality. Cereb Cortex, online ahead of print

Mühlig AK, Steingröver J, Heidelbach HS, Wingerath M, Sachs W, Hermans-Borgmeyer I, Meyer-Schwesinger C, Choi HY, Lim BJ, Patry C, Hoffmann GF, Endlich N, Bracke K, Weiß M, Guse AH, Lassé M, Rinschen M, Braun F, Huber TB, Puelles VG, Schmitt CP, Oh J (2022) The Calcium-Sensing Receptor Stabilizes Podocyte Function in Proteinuric Humans and Mice. Kidney Int., online ahead of print

Contact

University Medical Center Hamburg-Eppendorf 
Department of Biochemistry and Molecular Cell Biology 
Martinistrasse 52
20246 Hamburg

Scientific Coordinator

Dr. Björn-Philipp Diercks
Fon: +49  (0) 40 7410 54338
E-Mail: b.diercks©uke.de

Administration

Laura Mitsching
Fon: +49  (0) 40 7410 50301
E-Mail: l.mitsching©uke.de