SFB1328 2026
- 144 Weeks of bulevirtide monotherapy for chronic hepatitis D: Final and posttreatment results from a Phase 3 randomized trial
- Bile acid detergency as determinant of liver pathology in a humanized mouse model of progressive familial intrahepatic cholestasis type 3
- Single-cell omics and flow cytometry identify distinct immune states of dural and brain-infiltrating IL-17-producing γδ T cells after experimental stroke
- Twelve-week intermittent hypoxia intervention in multiple sclerosis - A safety and feasibility trial
- The conjugation-resistant bile acid norUDCA cures liver fibrosis but impairs systemic energy metabolism
- Downregulation of L-type Ca<sup>2+</sup> current in patients with atrial fibrillation results from altered channel gating and disruption of membrane microdomains
- Sex-specific roles of neuronal TNFR1 in synaptic remodeling and stroke recovery
- Targeting purinergic receptors in glioblastoma with nanobody-displaying AAV vectors
- Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling
- Effect of the intestinal microbiota on T<sub>H</sub>17 cell-derived cytokines in the context of intestinal inflammation
- Blimp-1 integrates alarmin signals in ILC2s and drives proinflammatory functions required for type 2 immunity
- IL-22 induces Paneth cell metaplasia in the colonic epithelium of ulcerative colitis, promoting wound healing via REG3A
- Stereotypical thinking in the historiography of science and religion: creation and reception history of Reijer Hooykaas's <em>Religion and the Rise of Modern Science</em>
- Integrative omics and phase IIa clinical trial identify TNF as key node in autoimmune hepatitis
- Fluorine-18-Labeled Nucleotide Analogs Targeting Ecto-5'-Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors
- RHOT Proteins Link Mitochondrial Motility to Cardiomyocyte Sarcomere Maturation
- From brown to white: Brown adipose tissue endothelial cells whiten in culture conditions
- Defining the vascular niche of human adipose tissue across metabolic states
- Immune austerity: How the body balances its books when calories run low
- Endothelial ADGRF5(GPR116) governs vascular adaptation required for sustained thermogenic remodeling of brown adipose tissue
- Advancing Raman Calibration: Automated Data Generation, Monitoring, and Control in Multi-Parallel Perfusion Mini Bioreactors
- Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure
- Emerging complexities of phospholipid metabolism in adipose tissue
- Oncostatin M upregulates CD73 via the MAPK pathway in keratinocytes to promote an adenosine-dependent anti-inflammatory response in psoriasis
- Extracellular Vesicle Properties and Functions Are Defined by the Originating Cell's Fitness Status
- Structural modeling and functional characterization of a novel gain-of-function TLR8 variant causing severe inflammatory syndrome
- ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models
- Adenosine-Specific Transcriptional Programs in Murine Connective Tissue-Type Mast Cells
- TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition
- Mutant KRAS in brain endothelial cells promotes vascular inflammation and impairs vascular integrity in brain arteriovenous malformation
- Inactivation of cofilin-1 in Mcpt5-Cre-nf-Cfl1<sup>fl/fl</sup> mice prevents the formation of connective tissue mast cells without affecting basophils: a new tool to investigate the specific role of CTMCs in disease
- A corona-like distribution and patchy pattern of cerebellar infarcts identify patients with giant cell arteritis
- Current perspective in acute ischemic stroke: net water uptake and imaging-guided selection as bridges to personalized, tissue-based care
- Development of a Fully Automated, High-Throughput Molecular Assay for Detection of Rat Hepatitis E Virus in Routine Diagnostics
- A new, machine learning-based approach to metastatic neuroendocrine tumors of unknown origin
- Cold exposure reduces trabecular and cortical bone mass in wildtype and Dio2-deficient mice
- Correction to: Associations of sphingosine‑1‑phosphate with soluble P‑selectin and adverse clinical outcome in patients with cerebral ischemia with and without acetylsalicylic acid treatment
- Endothelial oncogenic KRAS mutation drives the dynamics of microglia and macrophages in brain arteriovenous malformation
- Shiny-Calorie: a context-aware application for indirect calorimetry data analysis and visualization using R
- Refined fully automated RT-qPCR assay for simultaneous detection of SARS-CoV-2, Influenza A/B, and RSV with target optimization for improved variant resilience
- Consensus Review of Perioperative Immune Modulation for Endovascular Thrombectomy Following Ischemic Stroke
- Novel Bispecific Engagers Targeting the CεmX Domain of mIgE-Expressing Cells
- Perceptual measures of normal-hearing and hearing-impaired listeners across defined virtual acoustic scenes
- Phytochemical Screening of 45-Million-Year-Old Colored Angiosperm Leaves Reveals Distinctive Chlorophyll-Derived and Polyphenolic Pigments
- Antibiotic-Mediated Modulation of the Gut Microbiome Identifies Taurine as a Modulator of Adipocyte Function Through TGR5 Signaling
- Extended Duration of Anti-HEV IgM Seropositivity in Asymptomatic Blood Donors: Implications for Transfusion Safety
- Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease
- Distinct sympathetic projections to brown fat regulate thermogenesis and glucose tolerance
- A GDF-15-GFRAL axis controls autoimmune T cell responses during neuroinflammation
- Activating PRKG1 Variant Enhances Smooth Muscle Cell Deformability to Cause Aortopathy
- Proton-selective conductance and gating of the lysosomal cation channel TMEM175
- Multiple signaling events are required for NAADP synthesis by DUOX2 and formation of Ca<sup>2+</sup> microdomains to initiate T cell activation
- Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing
- Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry
- Trade-off between branching and polarity controls decision-making during cell migration
- Interpretation of Short RNA Thermal Unfolding Data Obtained by Circular Dichroism Using ChiraKit
- MOIS-SAM2: Exemplar-based segment anything model 2 for multi-lesion interactive segmentation of neurofibromas in whole-body MRI
- Risk of amyloid-related imaging abnormalities associated with anticoagulant therapy in patients with Alzheimer's disease treated with anti-amyloid monoclonal antibodies: a systematic review and meta-analysis
- Diet-derived microbial metabolites as regulators of immune function
- Trametinib Decreased Intracerebral Hemorrhages and Endothelial-to-Mesenchymal Transition in KRAS<sup>G12V</sup>-Induced Brain Arteriovenous Malformations in Mice
- Nuclear Ca<sup>2+</sup>-Calmodulin signaling in cardiac myocytes reduces catecholamine-evoked protein translation and prevents hypertrophy
- Blockade of Interleukin-6 Trans-signaling in the Presence of Certain Gut Microbiota Induces Mature-onset Obesity in Mice
- A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis
- Autoantibody-triggered podocyte membrane budding drives autoimmune kidney disease
- Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir
- Comparison of anti-human T cell globulins on immune reconstitution and early infections after autologous transplant in patients with multiple sclerosis
- Immune activation of primary human macrophages is suppressed by the coordinated action of <em>Yersinia</em> effectors
- Regulation of intestinal injury via dietary cysteine
- Discovery and characterization of quinoxaline and quinoline carboxamides as allosteric cannabinoid receptor modulators
- Fast enrichment and detection of circulating tumor cells from large volumes of whole blood of breast cancer patients utilizing a functionalized bioaffinity CTC filtration membrane
- Five-Year German PrEP cohort reveals high HIV protection and persistent STI burden: implications for individualized and flexible prevention strategies
- Associations of sphingosine-1-phosphate with soluble P-selectin and adverse clinical outcome in patients with cerebral ischemia with and without acetylsalicylic acid treatment
- A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD
- Dose Reduction in 4-Dimensional Computed Tomography Imaging: Breathing Signal-Guided Deep Learning-Driven Data Acquisition
- Preclinical Ischemic Stroke Multicenter Trials (PRISM) Collective Statement: Opportunities, Challenges, and Recommendations for a New Era