2021

2021

Hadaeghi F, Diercks BP, Schetelig D, Damicelli F, Wolf IMA, Werner R. Spatio-temporal feature learning with reservoir computing for T-cell segmentation in Ca2+ live-cell fluorescence microscopy. Sci Rep. 2021 Apr 15;11(1):8233.

Diercks BP, Jensen HH, Chalmers SB, Coode E, Vaughan MB, Tadayon R, Sáez PJ, Davis FM, Brohus M (2021) The first junior European Calcium Society meeting: calcium research across scales, Kingdoms and countries. BBA Mol Cell Res. 1868:118999.

Rissiek B, Heeren J, Koch-Nolte F, Mittrücker HW, Magnus T. (2021) Comment on "Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to Listeria monocytogenes". J Immunol. 206:667

Benzi A, Sturla L, Heine M, Fischer AW, Spinelli S, Magnone M, Sociali G, Parodi A, Fenoglio D, Emionite L, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S (2021) CD38 downregulation modulates NAD + and NADP(H) levels in thermogenic adipose tissues. Biochim Biophys Acta Mol Cell Biol Lipids 1866:158819

Guse AH, Gil Montoya DC, Diercks BP (2021) Mechanisms and functions of calcium microdomains produced by ORAI channels, d-myo-inositol 1,4,5-trisphosphate receptors, or ryanodine receptors. Pharmacol Ther 223:107804

Löhndorf A, Hosang L, Dohle W, Odoardi, Waschkowski SA, Marry S, Diercks BP, Flügel A, Guse AH (2021) 2-Methoxyestradiol and its derivatives inhibit store-operated Ca2+ entry in T cells: identification of a new and potent inhibitor. BBA - Molecular Cell Research 1868:118988

Diercks BP, Jensen HH, Chalmers SB, Coode E, Vaughan MB, Tadayon R, Sáez PJ, Davis FM, Brohus M (2021) The first junior European calcium society meeting: Calcium research across scales, kingdoms and countries. Biochim Biophys Acta Mol Cell Res, online ahead of print

Zhao C, Jia X, Schols D, Balzarini J, Meier C (2021) γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV. ChemMedChem 16:499-512

De Jong KA, Nikolaev VO (2021) Multifaceted remodelling of cAMP microdomains driven by different aetiologies of heart failure. FEBS J, online ahead of print

Woo MS, Ufer F, Rothammer N, Di Liberto G, Binkle L, Haferkamp U, Sonner JK, Engler JB, Hornig S, Bauer S, Wagner I, Egervari K, Raber J, Duvoisin RM, Pless O, Merkler D, Friese MA (2021) Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation. J Explodieren Med 218:e20201290

Woo MS, Steins D, Häußler V, Kohsar M, Haag F, Elias-Hamp B, Heesen C, Lütgehetmann M, Schulze Zur Wiesch J, Friese MA (2021) Control of SARS-CoV-2 infection in rituximab-treated neuroimmunological patients. J Neurol 268:5-7

Hildebrand S, Löwa N, Paysen H, Fratila RM, Reverte-Salisa L, Trakoolwilaiwan T, Niu Z, Kasparis G, Preuss SF, Kosch O, M de la Fuente J, Thanh NTK, Wiekhorst F, Pfeifer A (2021) Quantification of Lipoprotein Uptake in Vivo Using Magnetic Particle Imaging and Spectroscopy. ACS Nano 15:434-446

Fischer AW*, Jaeckstein MY*, Gottschling K, Heine M, Sass F, Mangels N, Schlein C, Worthmann A, Bruns OT, Yuan Y, Zhu H, Chen O, Ittrich H, Nilsson SK, Stefanicka P, Ukropec J, Balaz M, Dong H, Sun W, Reimer R, Scheja L, Heeren J (2021) Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation. Cell Metab 33:547-564 *shared first authors

Bertin E, Deluc T, Pilch KS, Martinez A, Pougnet JT, Doudnikoff E, Allain AE, Bergmann P, Russeau M, Toulmé E, Bezard E, Koch-Nolte F, Séguéla P, Lévi S, Bontempi B, Georges F, Bertrand SS, Nicole O, Boué-Grabot E (2021) Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice. Mol Psychiatry 26:629-644

Eggers M, Rühl F, Haag F, Koch-Nolte F (2021) Nanobodies as probes to investigate purinergic signaling. Biochem Pharmacol 114394

Lopez V, Schäkel L, Schuh HJM, Schmidt MS, Mirza S, Renn C, Pelletier J, Lee SY, Sévigny J, Alban S, Bendas G, Müller CE (2021) Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39. Mar Drugs 19:51

Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F (2021) Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. Br J Pharmacol 178:489-514

Wildner NH, Ahmadi P, Schulte S, Brauneck F, Kohsar M, Lütgehetmann M, Beisel C, Addo MM, Haag F, Schulze Zur Wiesch J (2021)B cell analysis in SARS-CoV-2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID-19. J Leukoc Biol 109:77-90

Calzaferri F, Narros-Fernández P, de Pascual R, de Diego AMG, Nicke A, Egea J, García AG, de Los Ríos C (2021) Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation. J Med Chem 64:2272-2290

Prades S, Heard G, Gale JE, Engel T, Kopp R, Nicke A, Smith KE, Jagger DJ (2021) Functional P2X 7 receptors in the auditory nerve of hearing rodents localize exclusively to peripheral glia. J Neurosci., online ahead of print

Roggenkamp HG, Khansahib I, Hernandez C LC, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla AV, Meier C, Fliegert R, Walseth TF, Flügel A, Diercks BP, Guse AH (2021) HN1L/JPT2: A signaling protein that connects NAADP generation to Ca 2+ microdomain formation. Sci Signal, online ahead of print

Fischer T, Prey J, Eschholz L, Rotermund N, Lohr C (2021) Norepinephrine-Induced Calcium Signaling and Store-Operated Calcium Entry in Olfactory Bulb Astrocytes. Front Cell Neurosci 15:639754

Schaltenberg N, John C, Heine M, Haumann F, Rinninger F, Scheja L, Heeren J, Worthmann A (2021) Endothelial Lipase Is Involved in Cold-Induced High-Density Lipoprotein Turnover and Reverse Cholesterol Transport in Mice. Front Cardiovasc Med 8:628235

Menzel S, Koudelka T, Rissiek B, Haag F, Meyer-Schwesinger C, Tholey A, Koch-Nolte F (2021) ADP-Ribosylation Regulates the Signaling Function of IFN-γ. Front Immunol 12:642545

Contact

University Medical Center Hamburg-Eppendorf 
Department of Biochemistry and Molecular Cell Biology 
Martinistrasse 52
20246 Hamburg

Scientific Coordinator

Dr. Björn-Philipp Diercks
Fon: +49  (0) 40 7410 54338
E-Mail: b.diercks©uke.de

Administration

Laura Mitsching
Fon: +49  (0) 40 7410 50301
E-Mail: l.mitsching©uke.de